Research

Your research can change the world

The IUPUI research community gives you the opportunity to make a difference, both locally and globally. Whether your idea engages a specific academic area or crosses disciplines, like STEM education, arts and humanities, integrated artificial intelligence, data science, and social, political, and life sciences, your idea could be the next big discovery that changes the world.

Recent research news

Portrait of Xiongbin Lu smiling at the camera.

Breast cancer research team finds game-changing drug

Xiongbin Lu, Ph.D., led the recently-published study to develop a new combination drug that treats triple negative breast cancer, which accounts for 15 percent of all breast cancer.

Explore what led to this breakthrough in treatment
Portrait of Becky Liu-Lastres smiling at the camera.

Pandemic forced female business travelers to change plans

A study from IUPUI's Becky Liu-Lastres, Amanda Cecil and Mona Mirehie weighed how female business travelers perceived and assumed risk during the pandemic, with the majority of women feeling somewhat unsafe taking business trips even as travel restrictions were lifted.

Explore how women approached travel risks
Portrait of Qingxue Zhang smiling at the camera.

IUPUI professor receives NSF grant for work on AI and Wearable Computing for Big Data Harnessing

Qingxue Zhang, Ph.D., leads the Ubiquitous Embedded Intelligence Lab (UbiEi Lab) to research, develop, and validate next-gen big data paradigms with people in mind. This 5-year CAREER award will target the many challenges found in analyzing and understanding big data.

Learn more about the NSF grant
Portrait of John Burns (left) and Kelsey Binion smiling at the camera.

The University Graduate School grants Distinguished Master’s Thesis Awards

Kelsey Binion and John Burns were recently selected as recipients of the 2020 awards for IUPUI. The Awards Committee of the Graduate Faculty Council considers such criteria as originality, documentation, significance, accuracy, organization, and style.

Read more about Kelsey and John's thesis awards

Discover the latest research news

The Research Enterprise is a monthly newsletter published by the office of the Vice Chancellor to keep the community informed about the latest creative and research endeavors at IUPUI.

Subscribe to the Research Enterprise

Description of the video:

[Music]

[Words appear: IU logo]

[Words appear: IUPUI]

[Words appear: 2020 Research Frontiers Trailblazer recipient]

[Words appear: IUPUI, OFFICE OF THEVICE CHANCELLOR FOR RESEARCH]

 

[Words appear: LIXIN WANG, PHD, Associate Professor, Earth Sciences]

[Video: Lixin is standing and is smiling at the camera.]

 

Lixin speaking: My field of research is ecohydrology, and essentially, I am interested in the interaction between vegetation dynamics and the water cycle.

 

[Video: the camera transitions to Lixin is sitting and speaking in the interview; the camera transitions to Lixin’s headshot from the side. Lixin is continuing his speaking.]

 

Lixin speaking: I think I'm always thinking about cutting edge questions in my field in terms of how vegetation impacts the climate, impacts the whole earth's system.

 

[Video: the camera transitions to Lixin is sitting and speaking in the interview; the camera transitions to Lixin is working with a white male in a lab, both wearing face masks; the camera transitions to a monito which displaying some signal graphics.]

 

Lixin speaking: Because while it is a big unknown question in the earth-science system, is how vegetation actually responds to the climate change and to regulate the climate. So my research will basically address the fundamental questions, how vegetation play a role in the whole system, and that will reduce our future predictions about impact of climate change on the whole earth.

 

[Video: the camera transitions to Lixin is sitting and speaking in the interview; the camera transitions to Lixin is wearing a face mask and is holding a stainless cup that has full of the soil, and moving it to a weight measure machine; the camera transitions to a hand holding a pen and writing some formula on a paper. ]

 

Lixin speaking: For example, I talk about drought impact for agriculture that is by example. Utilizing the knowledge of ecohydrology to helping the societal issue. At the same time, not only agriculture plant will be impacted, so natural plants, natural vegetation will also get impacted.

[Video: the camera transitions to Lixin’s headshot from the side. Lixin is continuing his speaking; the camera transitions to Lixin is working with another person is a lab, both are wearing face masks.]

Lixin speaking: For example, we have a project that is a forest response to. So we know forest is actually a big player in term of the global carbon cycle. Because forest, together with soil, they actually take up 30% of the global carbon we emit.

[Video: the camera transitions to Lixin is pointing and looking at a shelf that has many lab tubes on it; the camera transitions to a hand insert a lab tube into a lab tube collector.]

Lixin speaking: And when comes, that will reduce their capacity to actually take up the CO2. At same time we know some trees are different from others.

[Video: the camera transitions to Lixin is sitting and speaking in the interview;]

Lixin speaking: So basically it's a forest composition will actually impact the carbon sequestration of the whole forest. So my research actually try to understand how they can do that. Why is it do that? So we actually use some advanced technique to actually monitor their physiological response and try to understand why they do that.

[Video: the camera transitions to Lixin is walking on a hallway and is entering to his lab, and he is wearing a face mask.]

 Lixin speaking: Because I think only if we understand why they do that, we can then understand how do they response in the future.

[Music]

[Words appear: IU logo]

[Words appear: IUPUI]

[Words appear: IUPUI, OFFICE OF THE VICE CHANCELLOR FOR RESEARCH]

[Words appear: Filmed at the IUPUI Faculty Crossing]

[Music]

[End of Transcript]  

 

Description of the video:

[Music]

[Words appear: IU logo]

[Words appear: IUPUI]

[Words appear: Fulfilling the Promise]

[Words appear: EMPOWER]

[Words appear: Enhanced Mentoring Program with Opportunities for Ways to Excel in Research]

 

[Music]

[Words appear: What has been your primary challenge as a mentee?]

[Words appear: IUPUI, Joseph Tucker Edmonds, Mentee, Africana & Religious Studies]

[Video: Joseph is sitting with other two males; the camera transitions from Joseph is sitting with other two males to only Joseph.]

Joseph speaking: As a minority researcher I think that the main challenge that I faced in terms of mentoring and in terms of developing a research portfolio we are actually finding mentors who were interested in willing to engage you on the topic and so finding mentors that had the expertise the time and the resources to really draw you into their orbit and to share their lessons with you so that you could be successful during your tenure track.

 

[Music]

[Words appear: How has this experience positioned you to overcome these challenges?]

[Video: The camera transitions back to Joseph and other two males. One of two males are sitting with Joseph is now speaking. The male’s name later identifies as Cullen Merritt.]

[Words appear: IUPUI, Cullen Merritt, Mentee, School of Public & Environmental Affairs]

Cullen speaking: Phil has made numerous connections between me and other individuals within the university that I have benefited from and so that mentorship really becomes a community of mentors and I think that is at the forefront of higher education.

[Video: The camera transitions from Cullen is sitting with Joseph and the other male to Cullen only.]

Cullen speaking: if you want to advance if you want to be successful you have to find a community of mentors and not just a single person.

 

[Music]

[Words appear: What was your biggest surprise about the EMPOWER program and how have you benefited from working with both mentees?]

[Video: the third male now is speaking and later identifies as Philip Goff; the camera transitions from Philip is sitting Cullen and Joseph to only Philip; the camera transitions from only Philip to Philip, Cullen and Joseph sitting together.]

[Words appear: IUPUI, Philip Goff, Mentor, American & Religious Studies]

Philip speaking: You know academics we tend to be introverted and when you get a letter from the vice-chancellor saying we'd like you to meet one-on-one for a year with someone you don't know that well or someone you've never met before you know your throat seizes up like oh my god what but then the first time you sit down it becomes very quickly not just a professional conversation but a personal sharing and friendship of ideas.

[Video: The camera transitions from Philip is sitting Cullen and Joseph to only Philip; The camera transitions from only Philip to Philip, Cullen and Joseph sitting together.]

Philip speaking: because basically I ripped off these guys ideas all the time - they came in with new ideas new ways of thinking about things and sometimes they'd walk out and I think why didn't I ever do that I'm gonna start doing that so it's as a mentor you need to be ready to grow as well because you will.

 

[Music]

[Words appear: IU logo]

[Words appear:Sponpored by]

[Words appear: IUPUI, OFFICE OF THE VICE CHANCELLOR FOR RESEARCH]

[Words appear: IUPUI, OFFICE FOR WOMEN]

[Music]

[End of Transcript]

Description of the video:

[Music]

[Words appear: IU logo]

[Words appear: IUPUI]

[Words appear: 2020 Research Frontiers Trailblazer recipient]

[Words appear: IUPUI, OFFICE OF THEVICE CHANCELLOR FOR RESEARCH]

 

[Words appear: WENDY MILLER, PHD, RN, Associate Professor, Community & Health System]

[Video: Wendy is sitting on a chair and is facing at the camera speaking.]

 

Wendy speaking: So my research program is focused on improving self-management and quality of life for people with chronic diseases and specifically epilepsy. And my program of research really focuses on using the patient voice through big data and other methods to make sure that the interventions that we build are really focused on what's important to patients.

 

[Video: the camera transitions to focusing on Wendy’s headshot. Wendy is continuing her speaking.]

Wendy speaking: So capturing the patient voice is really important when you're building a behavioral intervention to improve outcomes.

 

[Video: the camera transitions to Wendy is walking on a hallway and then entering to a room; Wendy speaking: the camera transitions to focusing on Wendy’s headshot.]

And when I did my PhD and then my early career as a scientist, we relied on traditional methods like qualitative and then quantitative surveys and model testing. But what's really unique about my research now is that we have added to that the mining of social media data. So patients, when they have questions about their illness, not just in epilepsy, but in others, they will join a Facebook group. They will go to a foundation site like the Epilepsy Foundation and ask each other questions.

[Video: the camera transitions to Wendy is sitting in front of a computer workstation and focusing on the data on her monitor; the camera transitions to the monitor displaying some content; the camera transitions to a hand that is operating a mouse.]

Wendy speaking: So when you mine that data, it, the difference between that and the traditional methods is it's an organic type of data generation. There was no instrument through which that data came from the participant.

[Video: the camera transitions to Wendy is sitting in front of a computer workstation and focusing on the data on her monitor as the background. The foreground is an office title desk name plate that shows Wendy R. Miller, Ph.D.; the camera transitions to Wendy is sitting on a chair and is facing at the camera speaking.]

Wendy speaking: So it's actually in some cases more reliable and it doesn't rely on the researcher to know what to ask. So I did get some pushback initially because it is so new and sort of a strange way to do this type of research, but it has been extremely successful and shown us things that we didn't know that we're now building into interventions to help people with epilepsy.

[Video: the camera transitions to focusing on Wendy’s headshot. Wendy is continuing her speaking; the camera transitions to Wendy is sitting on a chair and is facing at the camera speaking; the camera again transitions to focusing on Wendy’s headshot. Wendy is continuing her speaking;]

Wendy speaking: Even though they have an illness, as a nurse, my perspective is getting them to their maximum level of functioning, even in the context of having that illness. So I think it's all about quality of life. So that is where this type of research can really be impactful.

 

[Video: the camera transitions to Wendy is walking on a hallway]

Wendy speaking: I really didn't know if we would find anything different in social media or other large data sets or Twitter. But I feel like here we have the freedom to be as innovative as we possibly can be because that's the only way that we're going to make these large gains.

[Music]

Words appear: IU logo]

[Words appear: IUPUI]

[Words appear: IUPUI, OFFICE OF THE VICE CHANCELLOR FOR RESEARCH]

[Words appear: Filmed at the IUPUI Faculty Crossing]

[Music]

[End of Transcript] 

Description of the video:

[MUSIC]

[Video: a man is speaking to the camera; the camera transitions to an image of a building; the camera transitions back to the man.]

A man speaks: At Integrated Nano systems Development Institute, me and my colleague Dr. Hamid Dalir are working on making reusable material that can capture and kill the virus.

[Video: while the man is speaking to the camera, words appear the man’s information]

[Words appear: Mangilal Agarwal, Director of the Integrated Nanosystems Development Institute]

[Video: while Mangilal still speaking in the background; the camera transitions to a researcher whom both hands are holding a mask; the camera transitions back to Mangilal; the camera transitions to a research whom both hands are holding a black mask; the camera transitions back to Mangilal.]

Mangilal speaks: Surgical masks can provide you protection with larger particles, but for a virus as small as 100 nanometer, they are not very effective to capture all the airborne virus particles. 

[Video: the camera focus on a microscope and then moving toward to a monitor which is displaying what is under the microscope; the camera transitions to a child who just sneeze with lots droplet; the camera transitions to the droplets turn to virus; the camera transitions to a machine that pulls paper layer; the camera transitions to a picture of Electrospun Nylon – 6.]

Mangilal speaks: To code this layer, we are using electrospinning technique that we have developed here at IUPUI. It is similar to like spray painting. 

[Video: The camera focus on Mangilal; the camera transitions to a machine in a lab.]

[Words appear: Vidya Wable, Graduate Student]

[Video: Vidya stands in front of a white board that has 7 images showing Electrosprayed. Vidya is pointing between images as she speaks; the camera transitions to a machine in the lab; the camera transitions to back to Vidya pointing between images.]

Vidya speaks: These are the nylon nanofibers, and these are the copper nanoparticles. When we electrospin and electrospray both simultaneously, it looks like this. So nylon traps the viruses, and copper kills the viruses.

[Words appear: Pias Kumar Biswas, INDI Research Assistant]

[Video: Pias and another male researcher are holding a mask while Pias speaks in front of camera.]

Pias speaks: Here you can see we have replaced the middle layer of the surgical mask, and we have modified them with our current technology, which is electrospun nylon fiber and electrosprayed copper oxide nanoparticle.

[Video: Camera focus on images on the white board; the camera transitions to the machine in the lab; the camera transitions to Mangilal.]

Mangilal speaks: You can apply this coating on any other substrate, HVAC filters at home or at commercial buildings, and also schools. We are also collaborating with local companies which are working on the Defense Protection Act to manufacture COVID-related PPE. 

[Video: Camera focus on Pias who is with the other male researcher working in the lab with few different machines; the camera transitions to Mangilal

Mangilal speaks IU Commercialization Office has been tremendous help. Since we disclosed this technology to their office, they have helped us to figure out how to start a company, filing the patent last year. 

[Video: a researcher is holding a black mask facing its inside to the camera; the camera transitions to a machine in the lab; the camera transitions to Mangilal.]

Mangilal speaks I think having a unit like ICO can make this happen, to work together, collaborate and succeed.  

[Words appear: IU logo]

[Words appear: Indiana University]

[Words appear: research.impact.iu.edu/coronavirus]

[MUSIC]

[End of Transcript]

Centers and institutes

Resources for today’s hot topics

Explore more centers and institutes