DB Last Updated: 2009-11-06 12:54:58
111
Transcription Factors |
110
Target Genes |
80
Mapped TFB sites |
396
TF Interactions
T Cell Stages
T Cell Stage
Surface markers
Rearrangements
Target Genes
CLP
IL-7R+, Lin-, Thy-1-, Sca-1(low), c-kit(low)
Flt3 Kit
DN1 (pro-T)
Cd44, CD117, c-kit, Cd4(low), CD25(neg), Thy-1(low), Sca-1
Il7r Cd5 Cd4 Ptcra Rag1 Rag2 Itgam Id2
Hes1 Myb Cd8a Dtx1
DN2 (pro-T)
Cd44, CD25, c-kit, Cd4(low), CD117,Thy-1, CD24
Ptcra Il7r Cd5 Cd4 Ifi205 Hes1 Dtx1 Cd44
Rag1 Id2 Itgam Rag2 Sfpi1 Cd8a
DN3 (pro-T)
Cd44(low), CD117(low), CD25
TCR-beta, gamma, delta
Il7r Cd5 Cd4 Ptcra Rag1 Rag2 Sfpi1 Cd8a
Dtx1
DN4 (pro-T)
CD25(neg), Cd44(neg)
TCR-alpha
Il7r Cd4 Ptcra Pim1 Cd8a Dtx1 Cd5
gamma-delta T (pre-DP)
Cd8a, CD3, gamma-delta TCR
Cd4 Tcrg
DP
Cd8a, alpha-beta TCR, Cd4, Cd69, Cd5, c-Kit(CD117)
alpha chain
Rag2 Cd4 Pim1 Smarcc1 Tcrg Cd8a Dntt Ada
Cd5 Bcl2 Il7r Cd44
SP (+8)
Cd8a, alpha-beta TCR
Cd4 Dtx1 Adam19 Ifi204 Gfi1 Fos Dusp1 Jun
Cd5 Cdkn1b Bcl2l11 Tlr2 Ifng Il2 Cd8a
SP (+4)
Cd4, alpha-beta TCR
Ifng Cd4 Dtx1 Adam19 Ifi204 Sell Gfi1 Il5
Fos Dusp1 Jun Gata3 Cd5 Tbx21 Il2
Bcl2
Regulatory T
Cd4+, CD25+, CTLA-4, GITR, CD103
Ifng Il4 Il7r Tnfrsf18 Ctla4 Itgae Il10 Il2
Th1
Cd4, Ifng receptor beta, IL-12R beta, IL-18R, P-selectin ligand 1
Il12a Ifng Il2 Il5 Bcl2 Il4
Th2
Cd4, T1/ST2, CCR3, CCR4, CCR8,
Fcer1g Il4 H2-Ab1 Il4ra Gata3 Il5 Ifng Il13
Ccl22 Il6 Cd4
