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LymphTF Databse: B cell developmental stages
DB Last Updated: 2009-11-06 12:54:58

111 Transcription Factors | 110 Target Genes | 80 Mapped TFB sites | 396 TF Interactions

B Cell Stages

B Cell Stage Surface markers Rearrangements Target genes
CLPIL-7R+, Lin-, Thy-1-, Sca-1(low), c-kit(low), AA4+, CD24(low), CD10
pre-pro-BLin-, AA4+, c-kit+, IL-7Ralpha, Ptprc+, CD24(low), Ia, CD148Ebf1 
early pro-Bcd45R, MHC II, Cd19, CD38, IL-7R+, Ia, CD148DJ (heavy )Il7r Pax5 Gfi1 Pim1 Cdkn1a Bcl2l1 Cish Socs1 
Cr2 Nfil3 Xbp1 Rag1 Rag2 Cd19 Igh 
Igj Ebf1 Cd79b Dntt Btnl2 Ccnd2 Cd79a 
Blnk Notch1 Csf1r Ptcra Blk Flt3 
late pro-Bcd45R, MHC class II, (Du), Cd19, CD38, IL-7R+, Ia, CD148DJ (heavy)Igll1 Il7r Pax5 Gfi1 Pim1 Cdkn1a Bcl2l1 Cish 
Socs1 Cr2 Nfil3 Xbp1 Rag1 Rag2 Cd19 
Igh Igj Ebf1 Cd79b Dntt Btnl2 Ccnd2 
Cd79a Blnk Csf1r Ptcra Blk Flt3 
large pre-Bcd45R, MHC class II, u, Cd19, CD20, CD38, pre-B cell Receptor, IL-7R+, Ia, CD148V(DJ) (heavy)Igll1 Vpreb1 Cd79a Btnl2 Cd79b Cr2 Igh-7 Blk 
Igh Gm1419 Ebf1 Il7r Rag1 Cd19 Igj 
Cdkn1b Bcl2l11 Rag2 Pax5 
small pre-Bcd45R, MHC class II, u, Cd19, CD20, CD38, pre-B cell Receptor, IL-7R+, Ia, CD148V(DJ) (heavy)Igll1 Vpreb1 Gm1419 Cd79a Btnl2 Cd79b Cr2 Blk 
Igh Ebf1 Il7r Rag1 Cd19 Igh-7 Igj 
Cdkn1b Bcl2l11 Rag2 Gfi1 Pax5 
immature Bcd45R, MHC class II, IgM, Cd19, CD20, CD21, Ia, CD148ยต (heavy), VJ (light)Igll1 Cdkn1b Prdm1 Cd19 Igh-7 Igh Igj Ccl3 
Ccnd2 Cd69 Cd44 Grap2 Icam1 Bcl2l11 Rag2 
Blk 
lymphoblastcd45R, MHC class II, Cd19, CD20, CD21, CD148Igh-7 
mature Bcd45R, MHC class II, IgM/IgD, Cd19, CD20, CD21, Ia, cd40, IL-R, B7, Cr2, Syndecan-1, CD148Igll1 Bcl2l1 Trp53 Cd5 Cd79a Syk Blnk C2ta 
Myc Bcl6 Prdm1 Cd80 Cd19 Igh-7 Igh 
Igj Ccl22 Il2rb Pim1 Aicda Cd44 Il6 
Fcer1g Rag2 Icam1 Fas Cr2 Cd72 Blk 
Cxcl2 
memory Bcd45R, MHC class II, IgG/IgA, Cd19, CD20, CD21, CD27, CD148, somatic hypermutationisotype switch (C alpha, gamma or epsilon)Irf4 Cd19 
plasma cellPlasma cell antigen-1, CD20, CD21, Syndecan-1, VLA-4, CXCR4Pax5 AY498738 H2-Ab1 Id3 Spib Xbp1 

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