DB Last Updated: 2009-12-02 12:14:52
111
Transcription Factors |
110
Target Genes |
78
Mapped TFB sites |
402
TF Interactions
B Cell Stages
B Cell Stage
Surface markers
Rearrangements
Target genes
CLP
IL-7R+, Lin-, Thy-1-, Sca-1(low), c-kit(low), AA4+, CD24(low), CD10
pre-pro-B
Lin-, AA4+, c-kit+, IL-7Ralpha, Ptprc+, CD24(low), Ia, CD148
Ebf1
early pro-B
cd45R, MHC II, Cd19, CD38, IL-7R+, Ia, CD148
DJ (heavy )
Il7r Pax5 Gfi1 Pim1 Cdkn1a Bcl2l1 Cish Socs1
Cr2 Nfil3 Xbp1 Rag1 Rag2 Cd19 Igh
Igj Ebf1 Cd79b Dntt Btnl2 Ccnd2 Cd79a
Blnk Notch1 Csf1r Ptcra Blk Flt3
late pro-B
cd45R, MHC class II, (Du), Cd19, CD38, IL-7R+, Ia, CD148
DJ (heavy)
Igll1 Il7r Pax5 Gfi1 Pim1 Cdkn1a Bcl2l1 Cish
Socs1 Cr2 Nfil3 Xbp1 Rag1 Rag2 Cd19
Igh Igj Ebf1 Cd79b Dntt Btnl2 Ccnd2
Cd79a Blnk Csf1r Ptcra Blk Flt3
large pre-B
cd45R, MHC class II, u, Cd19, CD20, CD38, pre-B cell Receptor, IL-7R+, Ia, CD148
V(DJ) (heavy)
Igll1 Vpreb1 Cd79a Btnl2 Cd79b Cr2 Igh-7 Blk
Igh Gm1419 Ebf1 Il7r Rag1 Cd19 Igj
Cdkn1b Bcl2l11 Rag2 Pax5
small pre-B
cd45R, MHC class II, u, Cd19, CD20, CD38, pre-B cell Receptor, IL-7R+, Ia, CD148
V(DJ) (heavy)
Igll1 Vpreb1 Gm1419 Cd79a Btnl2 Cd79b Cr2 Blk
Igh Ebf1 Il7r Rag1 Cd19 Igh-7 Igj
Cdkn1b Bcl2l11 Rag2 Gfi1 Pax5
immature B
cd45R, MHC class II, IgM, Cd19, CD20, CD21, Ia, CD148
ยต (heavy), VJ (light)
Igll1 Cdkn1b Prdm1 Cd19 Igh-7 Igh Igj Ccl3
Ccnd2 Cd69 Cd44 Grap2 Icam1 Bcl2l11 Rag2
Blk
lymphoblast
cd45R, MHC class II, Cd19, CD20, CD21, CD148
Igh-7
mature B
cd45R, MHC class II, IgM/IgD, Cd19, CD20, CD21, Ia, cd40, IL-R, B7, Cr2, Syndecan-1, CD148
Igll1 Bcl2l1 Trp53 Cd5 Cd79a Syk Blnk C2ta
Myc Bcl6 Prdm1 Cd80 Cd19 Igh-7 Igh
Igj Ccl22 Il2rb Pim1 Aicda Cd44 Il6
Fcer1g Rag2 Icam1 Fas Cr2 Cd72 Blk
Cxcl2
memory B
cd45R, MHC class II, IgG/IgA, Cd19, CD20, CD21, CD27, CD148, somatic hypermutation
isotype switch (C alpha, gamma or epsilon)
Irf4 Cd19
plasma cell
Plasma cell antigen-1, CD20, CD21, Syndecan-1, VLA-4, CXCR4
Pax5 AY498738 H2-Ab1 Id3 Spib Xbp1
