Indiana University School of Medicine
Animal Care and Use Application and Amendment Forms

Regulations require that an Institutional Animal Care and Use Committee (IACUC) approve all procedures involving the use of animals prior to their initiation. To comply with these regulations, an Indiana University School of Medicine (IUSM) Animal Care and Use Application Form must be completed.

The application form fulfills two purposes: 1) It allows the local IACUC to perform a federally mandated review of goals, protocols and procedures used in the proposed study to insure the humane treatment of animal subjects. 2) It serves as a record of the study protocols that can be reviewed by responsible outside agencies, such as AAALAC, USDA, FDA, or PHS. Therefore the application needs to be written clearly and concisely so that it is understandable by a broad audience of technical and non-technical reviewers. It is also advised that investigators carefully review each question and assure that the responses are complete. Incomplete narratives will delay approval of the proposed activities.

Application Forms (click links below)

• Class C Animals (Will not involve pain, distress, or use of pain-relieving drugs)
• Class D Animals (Will involve pain, distress but pain/distress will be modified or minor)
• Class E Animals (Will involve significant pain/distress.)
• Teaching Study (Animals will be used only for teaching or demonstration purposes.)

Amendment Form (click here)

Requirements, Processing, Deadlines, Misc. Information

• When is an Animal Care and Use Application Form Required?

• When is a Study Amendment Form Required?

• What changes do not require an Amendment Form?

• How do I add a new person to an existing study?

• The Review Process

• Deadlines

• Is Review by Designated Members of the IACUC possible?

• What are the requirements to conduct all of the proposed animal research activities in non-IUSM facilities?

• Instructions for Selecting the Appropriate Forms for a New Study

• Blank Forms & Instructions for Downloading & Submitting New Study and Amendment Forms

• Principal Investigator Responsibility for Documents