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  Sample Criteria for Euthanasia of Animals
  • Rapid weight loss (15-20% within a few days)
  • Extended period of weight loss progressing to emaciated state (spine becomes palpable in rodents)
  • Spreading area of alopecia caused by disease
  • Rough hair coat, hunched posture, distended abdomen, or lethargy, especially if debilitating or prolonged (3 days)
  • Diarrhea, especially if debilitating or prolonged (3 days) or unresponsive to treatment
  • Coughing, rapid or difficult breathing, rales, wheezing and nasal discharge
  • Distinct icterus and/or anemia
  • Rapid growth of mass or masses or clinical signs of neoplasia
  • Central nervous signs such as head tilt, tremors, spasticity, seizures, circling, paralysis or paresis, especially if associated with anorexia
  • Frank bleeding from any orifice
  • Markedly discolored urine, polyuria or anuria
  • Persistent self-induced trauma Lesions interfering with eating or drinking
  • Clinical signs of suspected infectious disease requiring necropsy for diagnosis

Examples:

The cut-off point for animals with neurological diseases should be chosen based upon the appearance of related symptoms, such as seizures or circling, when they interfere with eating and drinking.

Animals with tumors on the face should be euthanized when the skin overlying the tumors has ulcerated or there is evidence of persistent self-trauma

Approved by the School of Medicine Institutional Animal Care and Use Committee 9/96