SH/EAHP 2007 Workshop - Progress in T-cell and NK cell Malignancies - title graphic

Cases by Session

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Session 6. Extramedullary manifestation of neoplastic myeloid disorder

Session Chair Presented Case
Pileri - Presentation Link
Presented Cases
  • 012:
Chronic myelogenous leukemia in sudden blast crisis with an exclusively extramedullary presentation of precursor T lymphoblastic lymphoma.
  • 017:
Erythroblastic sarcoma.
  • 024:
AML with inv(16) (FAB AML-M4Eo) presenting as myeloid sarcoma of the submandibular gland and breast without bone marrow involvement.
  • 035:
Plasmacytoid Dendritic Cell Tumor/Leukemia (also refered to as CD4+CD56+ hematodermic neoplasm).
  • 073:
Extramedullary acute myeloid leukemia/Monoblastic sarcoma.
  • 101:
Intracranial myeloid sarcoma.
  • 179:
Extramedullary myeloid tumor involving brachial plexus and cerebrospinal fluid.
Other Cases in the Session
  • 010:
 Cervical LN: Classical example of uncommon case of MPD with turmor proliferation of plasmacytoid monocytes.
BM biopsy: Chronic myeloproliferative disorder (possibly CMML).
  • 042:
 Myeloid sarcoma with monocytic features and MLL rearrangment by FISH involving skin.
Atypical population of blasts with monocytic and monoblastic features involving the bone marrow, negative for MLL rearrangment, suspicious for early marrow involvement by acute myeloid leukemia.
  • 071:
 Myeloid sarcoma with histiocytic differentiation.
  • 108:
 Atypical chronic myeloid leukemia with differentiating extramedullary myeloid sarcoma.
Langerhans cell histiocytosis, involving skin and lymph nodes, clonally related to the atypical chronic myeloid leukemia.
  • 129:
 Acute myeloid leukemia with monocytic differentiation, presenting as a mediastinal mass and acute cardiac tamponade.
  • 130:
 Acute myelomonocytic leukemia, with extramedullary differentiation to interdigitating dendritic cell tumor.
  • 135:
 Biopsy #1: Granulocytic sarcoma, acute promyelocytic leukemia.
Biopsy #2: Acute promyelocytic leukemia (AML with t(15;17)(q22;q12)).
  • 136:
 Myeloid sarcoma with Chronic Myeloid Leukemia in the bone marrow, Chronic phase.
  • 142:
 Chronic myelomonocytic leukemia with associated extensive lymphadenopathy due to extramedullary hematopoiesis, likely representing involvement by chronic myelomonocytic leukemia.
  • 151:
 Myeloid sarcoma with megakacaryoblastic differentiation.
  • 159:
 Lymph node: Extramedullary hemopoiesis with marked pronormoblast proliferation, likely non-neoplastic.
Bone Marrow: Markedly hypercellular marrow with prominent pronormoblast proliferation, likely non-neoplastic.
  • 172:
 Plasmacytoid Dendritic Cell Tumor.
  • 173:
 Myeloid sarcoma/granulocytic sarcoma of ileum.
  • 204:
 Soft tissue of left foot: Granulocytic sarcoma with partial monocytic differentiation.
Bone marrow: Myeloproliferative/myelodysplastic disorder compatible with chronic myelomonocytic leukemia with excess blasts.
  • 207:
 Extramedullary Myeloid Tumor.
  • 210:
 Myeloid sarcoma involving the breast.
  • 212:
 Myeloproliferative/myelodysplastic syndrome with lymph node involvement and transformation to acute myeloid leukemia.
  • 221:
 Acute megakaryocytic leukemia.

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