| Session: Mast cell disease |
| Case number: 233 |
Submitter(s): H. F. Horny
Clinical history
52 year old female; pancytopenia
Details of gross/microscopic pathology:
Bone marrow with diffuse leukemic infiltration
Immunophenotype (flow cytometry/immunohistochemistry):
Blast cells: CD34+, CD56+; Mast Cells: tryptase+, KIT+, CD25-
Cytogenetics:
Molecular analysis:
D816Y-positive
Interesting feature(s) of submitted case:
Proposed diagnosis:
Myelomastocytic leukemia ?; SM-AML?
Panel diagnosis:
agree with proposed diagnosis
Comments:
Images:
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