| Session: Mast cell disease |
| Case number: 231 |
Submitter(s): H. F. Horny
Clinical history
64 year old male; skin tumor on the capillitium (relapsing since 6 years); no itching; Blood: unremarkable; Serum tryptase: 10,2; Whole body PET: unremarkable.
Details of gross/microscopic pathology:
Mast cell sarcoma of the skin (primary tumor); subtle infiltration of the bone marrow
Immunophenotype (flow cytometry/immunohistochemistry):
Tryptase+, KIT+, CD25+
Cytogenetics:
Molecular analysis:
D816V-negative
Interesting feature(s) of submitted case:
Proposed diagnosis:
Primary mast cell sarcoma of the skin
Panel diagnosis:
agree with proposed diagnosis
Comments:
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