From Evansville – 90 miles – 2 hours: I-64 East to SR 37 (Tell City exit 79) to French Lick

From Jefferson – 60 miles – 1 ¼ hours: I-64 West to US 150/SR 56 to French Lick

From Ft. Wayne – 230 miles – 4 hours: I-69 South to I-465 S to SR 37 to US 150/SR 56 to French Lick

From Gary – 255 miles – 4 ¼ hours: I-80 to I-65 South to I-465 S to SR 37 to US 150/SR 56 to French Lick

From South Bend – 250 miles – 4 ¾ hours: US 31 South to I-465 W to I-465 S to SR 37 to US 150/SR 56 to French Lick

From Indianapolis – 105 miles – 2 hours: Take SR 37 to US 150/SR 56 to French Lick