BBRC Pilot Projects

2013 Pilot Projects

PI

Co-PI/Co-I

Title

Burr

Bellido, Econs, Robling, Yokota

Development of NIAMS P30

Xie

Platt

Development of Novel Oral Stable Dental Resin Composite

Na

Yokota

FRET-Based Analysis of Mechanotransduction of Joint Cells

Li

Stat3 and Mitochondrial activity in Mechanotransduction

Lin

Synthetic Niche for In Vitro Culture of Pancreatic Cancer Cells

Wallace

Mechanical stimulation, fracture resistance and fracture healing in bone

Wu

Integration of Spatial and Temporal Respiratory Motion in Adaptive Proton Therapy Delivery

2014 Pilot Projects (First Round)

PI

Co-PI/Co-I

Title

Bruzzaniti

Chu

Pyk2 Inhibitor in Segmental Defect Bone Regeneration

Ji

Yokota

(no cost)

Mechanotransduction through the Nuclear Lamina in Cell Apoptosis under Fluid Shear Stress

Organ

Wallace

(no cost)

Biomechanical Effects of Low-Intensity, Multi-Directional Loading on Bone and Muscle Growth

Ryu

Na

Nanopattern-Driven Cell Migration: An Integrated Approach

Tu

Molecular Mechanisms Controlling Osteogenic Response to Mechanical Loading

2014 Pilot Projects (Second Round)

PI

Co-PI/Co-I

Title

Allen

Wallace

 

Enhancing Bone Mechanical Properties in Osteogenesis Imperfect through Combination Drug Treatment

Anwar

Chien, Warden

Yokota

Development of a Mechanical Knee Loading Device for Clinical Use

Li

Dai

 

Preliminary Study of Nrf2/Keap1 Signaling in Bone Metabolism and Mechanotransduction

Siegel

(INDI)

Naumann

Yokota

Designing a Drug Delivery System for Targeting Cancers in Bone