Welcome to the Bone Biology and Mechanics Lab
Welcome to the Bone Biology and Mechanics Lab (BBML) in the Department of Biomedical Engineering at Indiana University-Purdue University at Indianapolis (IUPUI). The BBML is committed to improving our understanding of how the body works through innovative research. Specifically, the laboratory is focused on investigating bone from mechanical engineering and materials science perspectives by tying morphology and composition to mechanical function and fracture resistance at discrete length scales throughout the hierarchy of bone (and other musculoskeletal tissues).
The long-term goal of the laboratory is to determine mechanisms by which biological and mechanical factors influence the mechanical integrity of bone at levels throughout the tissue’s hierarchy. Our goal is to translate findings into rational and clinically-relevant diagnostic and treatment options for defects, damage and disease of musculoskeletal tissues. A common thread that passes through all of our research projects is an interest in collagen and the roles collagen plays in bone health. Our research is currently funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the Indiana Clinical and Translational Sciences Institute (CTSI).