1

PUBLICATIONS

1. Inskeep, R.G. and Benson, M.D.: Further studies of the hexaquo chromium (III) ion ophenanthroline reaction. J. Inorg. Nucl. Chem. 20:290-294, 1961.

2. Krapcho, A.P. and Benson, M.D.: Ionic reactions in the spirane series. I. Effect of adjacent ring size on the acetolysis of neopentyl-type tosylates of the spirane series. J. Am. Chem. Soc. 84:1036, 1962.

3. Benson, M.D. and Cohen, A.S.: Antinuclear antibodies in systemic lupus erythematosus. Detection with horseradish- peroxidase-conjugated antibody. Ann. Intern. Med. 73:943-949, 1970.

4. Aldo, M.A., Benson, M.D., Comerford, F.R. and Cohen, A.S.: Treatment of Wegener's granulomatosis with immunosuppressive agents-Description of renal ultrastructure. Arch. Int. Med. 126:298-305, 1970.

5. Cathcart, E.S., Skinner, M., Lawless, O.J., Benson, M.D. and Cohen, A.S.: Antigenic determinants in amyloid deposits. Nature 228:1090-1091, 1970.

6. Cohen, A.S., Shirahama, T., Skinner, M., Benson, M.D. and Cathcart, E.S.: Ultrastructure and composition of amyloid - variable or constant. Protides of Biol. Fluids. XXth Symposium 73-80, 1972.

7. Shirahama, T., Benson, M.D., Cohen, A.S. and Tanaka, A.: Fibrillar assemblage of variable segments of immunoglobulin light chains - An electron microscopic study. J. Immunol. 110:21-30, 1973.

8. Benson, M.D. and Aldo, M.A.: Azathioprine therapy in polymyositis. Arch. Int. Med. 132:547-551, 1973.

9. Skinner, M., Cathcart, E.S., Cohen, A.S. and Benson, M.D.: Isolation and identification by sequence analysis of experimentally induced guinea pig amyloid fibrils. J. Exp. Med. 140:871-876, 1974.

10. Benson, M.D., Cohen, A.S., Brandt, K.D. and Cathcart, E.S.: Neuropathy, M-components and amyloid. Lancet 1:10-12, 1975.

11. Benson, M.D., Skinner, M. and Cohen, A.S.: Antigenicity and cross-reactivity of denatured fibril proteins of primary, secondary and myeloma associated amyloids. J. Lab. Clin. Med. 85:650-659, 1975.

12. Skinner, M., Benson, M.D. and Cohen, A.S.: Amyloid fibril protein related to immunoglobulin lambda chain. J. Immunol. 114:1433-1435, 1975.

13. Benson, M.D., Aldo-Benson, M.A., Shirahama, T., Borel, Y. and Cohen, A.S.: Suppression of in vitro antibody response by a serum factor (SAA) in experimentally induced amyloidosis. J. Exp. Med. 142:236-241, 1975.

14. Benson, M.D., Skinner, M., Lian, J.B. and Cohen, A.S.: "A" protein of amyloidosis: Isolation of a cross-reacting component from serum by affinity chromatography. Arthritis Rheum. 18:315-322, 1975.

15. Lessell, S., Wolf, P.A., Benson, M.D. and Cohen, A.S.: Scalloped pupils in familial amyloidosis. N. Engl. J. Med. 293:914-915, 1975.

16. Lian, J.B., Benson, M.D., Skinner, M. and Cohen, A.S.: A 25,000 molecular weight protein constituent of human amyloid fibrils related to amyloid protein AA. Arch. Biochem. Biophys. 171:197-205, 1975.

17. Benson, M.D., Skinner, M., Shirahama, T. and Cohen, A.S.: P-component of amyloid: Isolation from human serum by affinity chromatography. Arthritis Rheum. 19:749-754, 1976.

18. Block P.J., Skinner, M., Benson, M.D. and Cohen, A.S.: Identity of a peritoneal fluid immunoglobulin light chain and the amyloid fibril in primary amyloidosis. Arthritis Rheum. 19:755-759, 1976.

19. Scheinberg, M.A., Cathcart, E.S., Eastcott, J.W., Skinner, M., Benson, M.D., Shirahama, T. and Bennett, M.: The SJL/J mouse: A new model for spontaneous age-associated amyloidosis. Morphological and immunochemical aspects. Lab. Invest. 35:47-54, 1976.

20. Benson, M.D., Scheinberg, M.A., Shirahama, T., Cathcart, E.S. and Skinner, M.: Kinetics of serum amyloid protein in casein-induced murine amyloidosis. J. Clin. Invest. 59:412-417, 1977.

21. Lian, J., Skinner, M., Benson, M.D. and Cohen, A.S.: Fractionation of primary amyloid fibrils: Characterization and chemical interaction of the subunits. Biochem. Biophys. Acta 491:167-176, 1977.

22. Benson, M.D. and Cohen, A.S.: Generalized amyloid in a family of Swedish origin. A study of 426 family members in 7 generations of a new kinship with neuropathy, nephropathy and central nervous system involvement. Ann. Intern. Med. 86:419-424, 1977.

23. Skinner, M., Shirahama, T., Benson, M.D. and Cohen, A.S.: Murine amyloid protein AA in casein-induced experimental amyloidosis. Lab. Invest. 36:420-427, 1977.

24. Benson, M.D., Skinner, M. and Cohen, A.S.: Amyloid deposition in a renal transplant in familial Mediterranean fever. Ann. Intern. Med. 87:31-34, 1977.

25. Shirahama, T., Skinner, M., Cohen, A.S. and Benson, M.D.: Uncertain value of urinary sediments in the diagnosis of amyloidosis. N. Engl. J. Med. 297:821-823, 1977.

26. Benson, M.D. and Skinner, M.: Amino terminal sequence of amyloid P-component isolated from serum. J. Lab. Clin. Med. 92:78-83, 1978.

27. Benson, M.D. and Cohen, A.S.: Serum amyloid A protein in amyloidosis, rheumatic, and neoplastic diseases. Arthritis Rheum. 22:36-42, 1979.

28. Benson, M.D. and Aldo-Benson, M.A.: Effect of purified protein SAA on immune response in vitro: Mechanisms of suppression. J. Immunol. 122:2077-2082, 1979.

29. Scheinberg, M.A., Masuda, A., Benson, M.D. and Mendes, N.F.: Serum amyloid protein SAA, C-reactive protein and lysozyme in leprosy. Int. J. Lepr. 47: 133-137, 1979.

30. Kisilevsky, R., Benson, M.D., Axelrad, M.A. and Boudreau, L.: The effect of a liver protein synthesis inhibitor on plasma SAA levels in a model of accelerated amyloid deposition. Lab. Invest. 41:206-210, 1979.

31. Skinner, M., Vaitukaitis, J.L., Cohen, A.S. and Benson, M.D.: Serum amyloid P-component levels in amyloidosis, connective tissue diseases, infection, and malignancy as compared to normal serum. J. Lab. Clin. Med. 94:633-638, 1979.

32. Benson, M.D. and Kleiner, E.: Synthesis and secretion of serum amyloid protein A (SAA) by hepatocytes in mice treated with casein. J. Immunol. 124:495-499, 1980.

33. Rosenthal, J. and Benson, M.D.: Diffuse fasciitis and eosinophilia with symmetric polyarthritis. Ann. Intern. Med. 92:507-509, 1980.

34. Scheinberg, M.A., Hubscher, O., Morteo, O.G. and Benson, M.D.: Serum amyloid protein levels in South American children with rheumatoid arthritis: a cooperative study. Ann. Rheum. Dis. 39:228-230, 1980.

35. Eyanson, S., Passo, M.H., Aldo-Benson, M.A. and Benson, M.D.: Methylprednisolone pulse therapy for nonrenal lupus erythematosus. Ann. Rheum. Dis. 39:377-380, 1980.

36. Scheinberg, M.A. and Benson, M.D.: SAA amyloid protein levels in amyloid prone chronic inflammatory disorders. Lack of association with amyloid disease. J. Rheumatol. 7:724-726, 1980.

37. Kisilevsky, R. and Benson, M.D.: Serum amyloid A induction does not require the spleen. Lab. Invest. 44:84-86, 1981.

38. Benson, M.D.: Partial amino acid sequence homology between an heredofamilial amyloid protein and human plasma prealbumin. J. Clin. Invest. 67:1035-1041, 1981.

39. Kushner, I., Gewurz, H. and Benson, M.D.: C-reactive protein and the acute-phase response. J. Lab. Clin. Med. 97:739-749, 1981.

40. Aldo-Benson, M.A., Petersen, B.H. and Benson, M.D.: Suppression of in vitro antibody response of human peripheral blood lymphocytes by a heat labile factor in normal human serum. Clin. Exp. Immunol. 44:638-645, 1981.

41. Aldo-Benson, M.A. and Benson, M.D.: SAA suppression of immune response in vitro: Evidence for an effect on T cell-macrophage interaction. J. Immunol. 128:2390-2392, 1982.

42. Benson, M.D.: In vitro synthesis of the acute phase reactant SAA by hepatocytes. Ann. N.Y. Acad. Sci. 389:116-120, 1982.

43. Benson, M.D. and Aldo-Benson, M.A.: SAA suppression of in vitro antibody response. Ann. N.Y. Acad. Sci. 389:121-125, 1982.

44. Dwulet, F.E. and Benson, M.D.: Polymorphism of human plasma thyroxine binding prealbumin. Biochem. Biophys. Res. Commun. 114:657-662, 1983.

45. Eyanson, S. and Benson, M.D.: Erosive arthritis in hereditary amyloidosis. Arthritis Rheum. 26:1145-1149, 1983.

46. Benson, M.D. and Dwulet, F.E.: Prealbumin and retinol binding protein serum concentrations in the Indiana type hereditary amyloidosis. Arthritis Rheum. 26:1493-1498, 1983.

47. Dwulet, F.E. and Benson, M.D.: Primary structure of an amyloid prealbumin and its plasma precursor in a heredofamilial polyneuropathy of Swedish origin. Proc. Natl. Acad. Sci. USA 81:694-698, 1984.

48. Scheinberg, M.A., Pernambuco, J.C. and Benson, M.D.: DMSO and colchicine therapy in amyloid disease. Ann. Rheum. Dis. 43:421-423, 1984.

49. Benson, M.D. and Dwulet, F.E.: Identification of carriers of a variant plasma prealbumin (transthyretin) associated with familial amyloidotic polyneuropathy type I. J. Clin. Invest. 75:71-75, 1985.

50. Benson, M.D., Dwulet, F.E. and DiBartola, S.P.: Identification and characterization of amyloid protein AA in spontaneous canine amyloidosis. Lab. Invest. 52:448-452, 1985.

51 DiBartola, S.P., Benson, M.D., Dwulet, F.E. and Cornacoff, J.B.: Isolation and characterization of amyloid protein AA in the Abyssinian cat. Lab. Invest. 52:485-489, 1985.

52. Wallace, M.R., Naylor, S.L., Kluve-Beckerman, B., Long, G.L., McDonald, L., Shows, T.B. and Benson, M.D.: Localization of the human prealbumin gene to chromosome 18. Biochem. Biophys. Res. Commun. 129:753-758, 1985.

53. Dwulet, F.E., Strako, K. and Benson, M.D.: Amino acid structure of a lambda VI primary (AL) amyloid protein (WLT). Scand. J. Immunol. 22:653-660, 1985.

54. Dwulet, F.E., O'Conner, T.P. and Benson, M.D.: Polymorphism in a kappa I primary (AL) amyloid protein (BAN). Mol. Immunol. 23:73-78, 1986.

55. Benson, M.D., Eyanson, S. and Fineberg, N.: Serum amyloid A (SAA) in carcinoma of the lung. Cancer 57:1783-1787, 1986.

56. Benson, M.D.: Treatment of AL amyloidosis with melphalan, prednisone, and colchicine. Arthritis Rheum. 29:683-687, 1986.

57. Di Bartola, S.P., Tarr, M.J. and Benson, M.D.: Tissue distribution of amyloid deposits in Abyssinian cats with familial amyloidosis. J. Comp. Pathol. 96:387-398, 1986.

58. Wallace, M.R., Conneally, P.M., Long, G.L. and Benson, M.D.: Molecular detection of carriers of hereditary amyloidosis in a Swedish/American family. Am. J. Med. Genet. 25:335-341, 1986.

59. Benson, M.D., Dwulet, F.E., Scheinberg, M.A. and Greipp, P.: Chemical classification of hereditary amyloidosis in Brazilian families and identification of gene carriers. J. Rheumatol. 13:927-931, 1986.

60. Dwulet, F.E. and Benson, M.D.: Characterization of prealbumin variant associated with familial amyloidotic polyneuropathy type II (Indiana/Swiss). J. Clin. Invest. 78:880-886, 1986.

61. Wallace, M.R., Dwulet, F.E., Conneally, P.M. and Benson, M.D.: Biochemical and molecular genetic characteristic of a new variant prealbumin associated with hereditary amyloidosis. J. Clin. Invest. 78:6-12, 1986.

62. Kluve-Beckerman, B., Long, G.L. and Benson, M.D.: DNA sequence evidence for polymorphic forms of human serum amyloid A (SAA). Biochem. Genet. 24:795-803, 1986.

63. Kluve-Beckerman, B., Naylor, S.L., Marshall, A., Gardner, J.C., Shows, T.B. and Benson, M.D.: Localization of human SAA gene(s) to chromosome 11 and detection of DNA polymorphisms. Biochem. Biophys. Res. Commun. 137:1196-1204, 1986.

64. Refetoff, S., Dwulet, F.E. and Benson, M.D.: Reduced affinity for thyroxine in two of three structural thyroxine-binding prealbumin (TBPA) variants associated with familial amyloidotic polyneuropathy. J. Clin. Endocrinol. Metab. 63:1432-1437, 1986.

65. Hernandes, C.E.H., Scheinberg, M.A., Benson, M.D. and Finkelstein, A.E.: The effect of gold salts on casein-induced macrophage activation and serum amyloid protein SAA levels. Clin. Exp. Rheumatol. 4:347-350, 1986.

66. Benson, M.D., Wallace, M.R., Tejada, E., Bauman, H. and Page, B.: Hereditary amyloidosis: Description of a new American kindred with late onset cardiomyopathy. Arthritis Rheum. 30:195-200, 1987.

67. Dwulet, F.E. and Benson, M.D.: Primary structure of amyloid fibril protein AA in azocasein-induced amyloidosis of CBA/J mice. J. Lab. Clin. Med. 110:322-329, 1987.

68. Wallace, M.R., Dwulet, F.E., Williams, E.C., Conneally, P.M. and Benson, M.D.: Identification of a new hereditary amyloidosis prealbumin variant, tyr77, and detection of the gene by DNA analysis. J. Clin. Invest. 81:189-193, 1988.

69. Dwulet, F.E., Wallace, D.K. and Benson, M.D.: Amino acid structures of multiple forms of amyloid-related serum protein SAA from a single individual. Biochemistry 27:1677-1682, 1988.

70. Kluve-Beckerman, B., Dwulet, F.E. and Benson, M.D.: Human serum amyloid A: three hepatic mRNAs and the corresponding proteins in one person. J. Clin. Invest. 82:1670-1675, 1988.

71. Wallace, M.R., Conneally, P.M. and Benson, M.D.: A DNA test for Indiana/Swiss hereditary amyloidosis (FAP II). Am. J. Hum. Genet. 43:182-187, 1988.

72. Benson, M.D.: Reactive (secondary) amyloid and its protein precursor. J. Lab. Clin. Med. 112:405-406, 1988.

73. Nichols, W.C., Dwulet, F.E., Liepnieks, J. and Benson, M.D.: Variant apolipoprotein AI as a major constituent of a human hereditary amyloid. Biochem. Biophys. Res. Commun. 156:762-768, 1988.

74. Jacobelli, S., Vial, S., Rosenberg, H., Benson, M.D. and Scheinberg, M.A.: Amyloidosis secondary to gout. Identification with a monoclonal antibody to amyloid protein A. Clin. Rheumatol. 7:534-537, 1988.

75. Glueck, H.I., Coots, M.D., Benson, M.D., Dwulet, F.E. and Hurtubise, P.E.: A monoclonal immunoglobulin A (K) factor VIII: C inhibitor associated with primary amyloidosis: Identification and characterization. J. Lab. Clin. Med. 113:269-277, 1989.

76. Harats, N., Worth, R. and Benson, M.D.: Spinal claudication in systemic amyloidosis. J. Rheum. 16:1003-1006, 1989.

77. DiBartola, S.P., Reiter, J.A., Cornacoff, J.B., Kociba, G.J. and Benson, M.D.: Serum amyloid A protein concentration measured by radial immunodiffusion in Abyssinian and non-Abyssinian cats. Am. J. Vet. Res. 50:1414-1417, 1989.

78. Harats, N., Kluve-Beckerman, B., Passo, M., Quinn, L. and Benson, M.D.: Lack of association of a restriction fragment length polymorphism for serum amyloid P gene with reactive amyloidosis. Arthritis Rheum. 32:1325-1327, 1989.

79. Benson, M.D., Dwulet, F.E., Madura, D. and Wheeler, G.: Amyloidosis related to a lambda IV immunoglobulin light chain protein. Scand. J. Immunol. 29:175-179, 1989.

80. Brinckerhoff, C.E., Mitchell, T.I., Karmilowicz, M.L., Kluve-Beckerman, B. and Benson, M.D.: Autocrine induction of collagenase in fibroblasts by serum amyloid-like and B₂-microglobulin-like proteins. Science 243:655-657, 1989.

81. Kincaid, J.C., Wallace, R.W. and Benson, M.D.: Late onset familial amyloid polyneuropathy in an American family of English origin. Neurology 39:861-863, 1989.

82. Carothers, M.A., Johnson, G.C., DiBartola, S.P., Liepnieks, J. and Benson, M.D.: Extramedullary plasmacytoma and immunoglobulin-associated amyloidosis in a cat. J. Am. Vet. Med. Assoc. 195:1593-1597, 1989.

83. Kluve-Beckerman, B., Dwulet, F.E., DiBartola, S.P. and Benson, M.D.: Primary structures of dog and cat amyloid A proteins: Comparison to human AA. Comp. Biochem. Physiol. 94B:175-183, 1989.

84. Nichols, W.C., Padilla, L.-M. and Benson, M.D.: Prenatal detection of a gene for hereditary amyloidosis. Am. J. Med. Genet. 34:520-524, 1989.

85. Nichols, W.C., Liepnieks, J.J., McKusick, V.A. and Benson, M.D.: Direct sequencing of the gene for Maryland/German familial amyloidotic polyneuropathy type II and genotyping by allele-specific enzymatic amplification. Genomics 5:535-540, 1989.

86. Harats, N., Worth, R.M. and Benson, M.D.: Hereditary amyloidosis: Evidence against early amyloid deposition. Arthritis Rheum. 32:1474-1476, 1989.

87. DiBartola, S.P. and Benson, M.D.: The pathogenesis of reactive systemic amyloidosis. J. Vet. Int. Med. 3:31-41, 1989.

88. Nichols, W.C. and Benson, M.D.: Hereditary amyloidosis: Detection of variant prealbumin genes by restriction enzyme analysis of amplified genomic DNA sequences. Clin. Genet. 37:44-53, 1990.

89. Morris, M., Nichols, W.C. and Benson, M.D.: Prenatal diagnosis of hereditary amyloidosis in a Portuguese family. Am. J. Med. Genet. 39:123-124, 1991.

90. Liepnieks, J.J., Dwulet, F.E. and Benson, M.D.: Amino acid sequence of a kappa I primary (AL) amyloid protein (AND). Mol. Immunol. 27:481-485, 1990.

91. Nichols, W.C., Gregg, R.E., Brewer, H.B. and Benson, M.D.: A mutation in apolipoprotein A-I in the Iowa type of familial amyloidotic polyneuropathy. Genomics 8:318-323, 1990.

92. Mendell, J.R., Jiang, X-S, Warmolts, J.R., Nichols, W.C., and Benson, M.D.: Diagnosis of Maryland/ German Familial Amyloidotic Polyneuropathy (FAP II) using allele-specific enzymatically amplified genomic DNA. Ann. Neurol. 27:553-557, 1990.

93. Koeppen, A.H., Wallace, M.R., Benson, M.D., and Altland, K.: Familial amyloid polyneuropathy: Alanine-for-threonine substitution in the transthyretin (prealbumin) molecule. Muscle Nerve 13:1065-1075, 1990.

94. Moses, A.C., Rosen, H.N., Moller, D.E., Tsuzaki, S., Haddow, J.E., Lawlor, J., Liepnieks, J.J., Nichols, W.C. and Benson, M.D.: A point mutation in transthyretin increases affinity for thyroxine and produces euthyroid hyperthyroxinemia. J. Clin. Invest. 86:2025-2033, 1990.

95. Liauw, L., Brandt, K.D., Benson, M.D., Aldo-Benson, M., Spindler, J.S., Wilkens, J.D., Moscaritola, K., Chan, E.Ku and Quagliata, F.: Synovial fluid and plasma drug levels and effects on eicosanoid metabolism of diclofenac sodium in patients with rheumatoid arthritis and osteoarthritis. Seminars in Arthritis and Rheumatism, 15:65-67, 1989.

96. Schaefer, J.R., Rader, D.J., Gregg, R.E., Fairwell, T., Zech, L.A., Kindt, M.R., Benson, M.D. and Brewer, Jr., H.B.: The use of stable isotopes and mass spectrometry in the investigation of the in vitro metabolism of mutant proteins in humans. (Submitted.)

97. Rader, D.J., Gregg, R.E., Meng, M.S., Schaefer, J.R., Kindt, M.R., Zech, L.A., Benson, M.D. and Brewer, Jr., H.B.: In vivo metabolism of a mutant apolipoprotein, apoA-I_Iowa, associated with hypoalphalipoproteinemia and hereditary systemic amyloidosis. J. Lipid Res. 33:755-763, 1992.

98. Satier, F., Nichols, W.C. and Benson, M.D.: Diagnosis of familial amyloidotic polyneuropathy in France. Clin. Genet. 38:469-473, 1990.

99. Nichols, W.C., Liepnieks, J.J., Snyder, E. L. and Benson, M.D.: Senile cardiac amyloidosis associated with homozygosity for a transthyretin variant (Ile-122). J. Lab. Clin. Med. 117:175-180, 1991.

100. Kluve-Beckerman, B., Drumm, M. and Benson, M.D.: Nonexpression of the human serum amyloid A three (SAA3) gene. DNA and Cell Biology 10:651-661, 1991.

101. Harrison, H.H., Gordon, E.D., Nichols, W.C., and Benson, M.D.: Biochemical and clinical characterization of prealbumin^Chicago: A benign variant of serum prealbumin (transthyretin) discovered with high resolution, two dimensional electrophoresis. Am. J. Med. Gen. 39:442-452, 1991.

102. Martone, R.L., Benson, M.D., Schon, E.A., and Herbert, J.: Transthyretin-amyloid from vitreous contains myelin protein P2: Implications for amyloid fibrillogenesis. (Submitted.)

103. Liepnieks, J.J., Dwulet, F.E., Benson, M.D., Kluve-Beckerman, B. and Kushner, I.: The primary structure of serum amyloid A protein in the rabbit: Comparison with serum amyloid A proteins in other species. J. Lab. Clin. Med. 118:570-575, 1991.

104. Hamilton, J.A., Steinrauf, L.K., Liepnieks, J.J., Benson, M.D., Holmgren, G., Sandgren, O. and Steen, L.: Alteration in molecular structure which results in disease: The Met-30 variant of human plasma transthyretin. Biochim. Biophys. Acta, 1139:9-16, 1992.

105. Murrell, J., Farlow, M., Ghetti, B. and Benson, M.D.: A mutation in the amyloid precursor protein (APP) associated with hereditary Alzheimer's disease. Science 254:97-99, 1991.

106. Steinrauf, L.K., Cao, Y., Hamilton, J., Murrell, J., Liepnieks, J.J. and Benson, M.D.: Preparation and crystallization of human transthyretin (prealbumin) variants. Biochem. Biophys. Res. Commun. 179:804-809, 1991.

107. Ghetti, B., Murrell, J., Benson, M.D. and Farlow, M.: Spectrum of amyloid b-protein immunoreactivity in hereditary Alzheimer disease with a guanidine to thymidine missense change at position 1924 of the APP gene. Brain Res. 571:133-139, 1992.

108. Murrell, J.R., Schoner, R.G., Liepnieks, J.J., Rosen, H.N., Moses, A.C. and Benson, M.D.: Production and functional analysis of normal and variant recombinant human transthyretin proteins. J. Biol. Chem. 267:16595-16600, 1992.

109. Steinrauf, L.K., Hamilton, J.A., Braden, B.C., Murrell, J.R. and Benson, M.D.: X-ray crystal structure of the Ala-1096Thr variant of human transthyretin which produces euthyroid hyperthyroxinemia. J. Biol. Chem. 268: 2425-2430, 1993.

110. Kluve-Beckerman, B., Malle E., Vitt, H., Pfeiffer, C., Benson, M.D., and Steinmetz, A.: Characterization of an isoelectric focusing variant of SAA1 (Asp-72) in a family of Turkish origin. Biochem. Biophys. Res. Commun. 181:1097-1102, 1991.

111. Uemichi, T., Gertz, M.A., and Benson, M.D.: Amyloid polyneuropathy in two German-American families: A novel transthyretin variant (Val-107). J. Med. Genet. 31:416-417, 1994.

112. Rosen, H.N., Moses, A.C., Murrell, J.R., Liepnieks, J.J., Holmgren, G., Sandgren, O., Steen, L. and Benson, M.D.: Thyroxine interactions with transthyretin: A comparison of 10 different naturally-occurring transthyretin variants. J. Clin. Endo. Metab. 77:370-374, 1993.

113. Uemichi, T., Murrell, J.R., Zeldenrust, S., and Benson, M.D.: A new mutant transthyretin (Arg 10) associated with familial amyloid polyneuropathy. J. Med. Genet. 29:888-891, 1992.

114. Benson II, M.D., Julien, J., Liepnieks, J., Zeldenrust, S., and Benson, M.D.: A transthyretin variant (Alanine 49) associated with familial amyloidotic polyneuropathy in a French family. J. Med. Genet., 30:117-119, 1993.

115. Benson II, M.D., Turpin, J.C., Lucotte, G., Zeldenrust, S., LeChevalier, B., and Benson, M.D.: A transthyretin variant (alanine 71) associated with familial amyloidotic polyneuropathy in a French family. J. Med. Genet. 30: 120-122, 1993.

116. Farlow, M., Murrell, J., Ghetti, B., Unverzagt, F., Zeldenrust, S. and Benson, M.D.: Clinical characteristics in a kindred with early onset Alzheimer's disease and their linkage to a G6T change at position 2149 of amyloid-precursor protein. Neurology 44:105-111, 1994.

117. Zeldenrust, S.R., Murrell, J., Farlow, M., Ghetti, B., Roses, A.D. and Benson, M.D.: RFLP analysis for APP 717 mutations associated with Alzheimer's disease. J. Med. Genet. 30:476-478, 1993.

118. Zeldenrust, S.R., Skinner, M., Harding, J., Skare, J., and Benson, M.D.: A new transthyretin variant (His 69) associated with vitreous amyloid in an FAP family. Amyloid: Int. J. Exp. Clin. Invest. 1:17-22, 1994.

119. Benson, M.D., Liepnieks, J., Uemichi, T., Wheeler, G. and Correa, R.: Hereditary renal amyloidosis associated with a mutant fibrinogen a-chain. Nature Genet. 3:252-255, 1993.

120. Hamilton, J.A., Steinrauf, L.K., Braden, B.C., Liepnieks, J.J., Benson, M.D., Holmgren, G., Sandgren, O. and Steen, L.: The X-ray crystal structure refinements of normal human transthyretin and the amyloidogenic Val-306Met variant to 1.7Å resolution. J. Biol. Chem. 268:2416-2424, 1993.

121. Farlow, M., Ghetti, B., Benson, M.D., Farrow, J.S., Van Nostrand, W.E. and Wagner, S.L.: Low cerebrospinal-fluid concentrations of soluble amyloid ß-protein precursor in hereditary Alzheimer's disease. Lancet 340:453-454, 1992.

122. Kluve-Beckerman, B., Song, M., Benson, M.D., and Liepnieks, J.J.: Recombinant murine serum amyloid A from baculovirus-infected insect cells: Purification and characterization. Biochim. Biophys. Acta 1182:303-310, 1993.

123. Steiner, R.D., Paunio, T., Uemichi T., Evans, J.P., Benson, M.D.: Asp187Asn mutation of gelsolin in an American kindred with familial amyloidosis, Finnish type (FAP IV). Human Genet. 95:327-330, 1995.

124. Braden, B.C., Steinrauf, L.K., Clawson, D., Hamilton, J.A., Murrell, J.R., and Benson, M.D.: Two naturally occurring variants of TTR have different affinities for thyroxine: Comparison of the crystal structures of the complexes with thyroxine. (Submitted).

125. Hamilton, J.A., Steinrauf, L.K., Braden, B.C., Murrell, J.R., and Benson, M.D.: Structural changes in transthyretin produced by the Ile84Ser mutation which result in decreased affinity for retinol-binding protein and thyroxine. Amyloid: Int. J. Exp. Clin. Invest. 3:1-12, 1996.

126. Liepnieks, J.J., Ghetti, B., Farlow, M.J., Roses, A.D., and Benson, M.D.: Characterization of amyloid fibril ß-peptide in familial Alzheimer's disease with APP717 mutations. Biochem. Biophys. Res. Commun. 197:386-392, 1993.

127. Rosen, H.N., Murrell, J.R., Liepnieks, J.J., Benson, M.D., Cody, V., and Moses, A.C.: Threonine-for-alanine substitution at position 109 of transthyretin differentially alters TTR's affinity for iodothyronines. Endocrinology 134:27-34, 1994.

128. Uemichi, T., Liepnieks, J.J., and Benson, M.D.: Hereditary renal amyloidosis with a novel variant fibrinogen. J. Clin. Invest. 93:731-736, 1994.

129. Colley, A., Zeldenrust, S., and Benson, M.D.: Familial amyloidotic polyneuropathy: An Australian family with the alanine-60 transthyretin gene mutation. (Submitted).

130. Yamada, T., Kluve-Beckerman, B., Kuster, W.M., Liepnieks, J.J., and Benson, M.D.: Measurement of serum amyloid A₄ (SAA₄); Its constitutive presence in serum. Amyloid: Int. J. Exp. Clin. Invest. 1:114-118, 1994.

131. Saunders, A.M., Schmader, K., Breitner, J.C., Benson, M.D., Brown, W.T., Goldfard, L., Goldgaber, D., Manwaring, M.G., Szymanski, M.H., McCrown, N., Dole, K.C., Schmechel, D.E., Strittmatter, W.J., Pericak-Vance, M.A., and Roses, A.D.: Apolipoprotein E e4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases. Lancet 342:710-711, 1993.

132. Yamada, T., Kluve-Beckerman, B., Liepnieks, J.J., and Benson, M.D.: Fibril formation from recombinant human serum amyloid A. Biochimica et Biophysica Acta 1226:323-329, 1994.

133. Uemichi, T., Liepnieks, J.J., Altland, K., and Benson, M.D.: Identification of a novel non-amyloidogenic transthyretin polymorphism (His-74) in the German population. Amyloid: Int. J. Exp. Clin. Invest. 1:149-153, 1994.

134. Zeldenrust, S., and Benson, M.D.: A new test for detection of the His-58 variant transthyretin allele in hereditary amyloidosis. Amyloid: Int. J. Exp. Clin. Invest. 1:154-159, 1994.

135. Zhao, N. Aoyama, N, Benson, M.D., Skinner, M., Satier, F., and Sakaki, Y.: Haplotype analysis of His58, Ala60 and Tyr77 types of familial amyloidotic polyneuropathy. Amyloid: Int. J. Exp. Clin. Invest. 1:75-79, 1994.

136. Zólyomi, Z., Benson, M.D., Halász, K., Uemichi, T., Fekete, G.: Transthyretin mutation (Serine 84) associated with familial amyloid polyneuropathy in a Hungarian family. Amyloid: Int. J. Exp. Clin. Invest. 5:30-34, 1998.

137. Liepnieks, J.J., Kluve-Beckerman, B., and Benson, M.D.: Characterization of amyloid A protein in human secondary amyloidosis: The predominant deposition of serum amyloid A1. Biochimica et Biophysica Acta 1270:81-86, 1995.

138. Eilam, O., Liepnieks, J., Weisberger, E., and Benson, M.D.: Plasmacytoma of the nasal cavity with lambda III amyloid deposition. Amyloid: Int. J. Exp. Clin. Invest. 2:31-35, 1995.

139. Berni, R., Malpeli, G., Folli, C., Murrell, J., Liepnieks, J.J., and Benson, M.D.: The Ile-846Ser amino acid substitution in transthyretin interferes with the interaction with plasma retinol-binding protein. J. Biol. Chem. 269:23395-23398, 1994.

140. Uemichi, T., Waits, R.P., Murrell, J.R., Farlow, M., Ghetti, B., and Benson, M.D.: DNA diagnosis of familial Alzheimer's disease using polymorphic microsatellite analysis. (Submitted).

141. Yamada, T., Liepnieks, J.J., Kluve-Beckerman, B., and Benson, M.D.: Cathepsin B generates the most common form of amyloid A (76 Residues) as a degradation product from serum amyloid A. Scand. J. Immunol. 41:94-97, 1995.

142. Uemichi, T., Gertz, M.A., and Benson, M.D.: A new transthyretin variant (Ser 24) associated with familial amyloid polyneuropathy. J. Med. Genet. 32:279-281, 1995.

143. Lippa, C.F., Saunders, A.M., Smith, T.W., Swearer, J.M., Drachman, D.A., Ghetti, B., Nee, L., Pulaski-Salo, D., Dickson, D., Robitaille, Y., Bergeron, C., Crain, B., Benson, M.D., Farlow, M., Hyman, B.T., St. George-Hyslop, P., Roses, A.D., Pollen, D.A.: Familial and sporadic Alzheimer's disease: Neuropathology cannot exclude a final common pathway. Neurology 46:406-412, 1996.

144. Waits, R.P., Uemichi, T., and Benson, M.D.: Haplotype analysis of the transthyretin gene: Evidence for multiple recurrence of the Met30 mutation in the Caucasian population. Amyloid: Int. J. Exp. Clin. Invest. 2:114-118, 1995.

145. Almeida, M.R., Oishi, K., Sakaki, Y., Holmgren, G., Drugge, U., Ferlini, A., Salvi, F., Munar-Qués, M., Benson, M.D., Skinner, M., Costa, P.P., and Saraiva, M.J.: Haplotype analysis of common transthyretin mutations. Hum. Genet. 96:350-354, 1995.

146. Yamada, T., Kluve-Beckerman, B., Liepnieks, J.J., and Benson, M.D.: In vitro degradation of serum amyloid A by cathepsin D and other acid proteases: Possible protection against amyloid fibril formation. Scand. J. Immunol. 41:570-574, 1995.

147. Schormann, N., Murrell, J.R., and Benson, M.D.: Tertiary structures of amyloidogenic and non-amyloidogenic transthyretin variants: new model for amyloid fibril formation. Amyloid: Int. J. Exp. Clin. Invest. 5:175-187, 1998.

148. Waits, R.P., Yamada, T., Uemichi, T., and Benson, M.D.: Low plasma concentrations of retinol-binding protein in individuals with mutations affecting position 84 of the transthyretin molecule. Clin. Chem., 41:1288-1291, 1995.

149. Schormann, N., Murrell, J.R., Liepnieks, J.J., and Benson, M.D.: Tertiary structure of an amyloid immunoglobulin light chain protein: A proposed model for amyloid fibril formation. Proc. Natl. Acad. Sci. USA 92:9490-9494, 1995.

150. Liepnieks, J.J., DiBartola, S.P., Benson, M.D.: Systemic immunoglobulin (AL) amyloidosis in a cat: Complete primary structure of a feline lambda light chain. Amyloid: Int. J. Exp. Clin. Invest. 3:177-182, 1996.

151. Yamada, T., Liepnieks, J., Benson, M.D., and Kluve-Beckerman, B.: Accelerated amyloid deposition in mice treated with the aspartic protease inhibitor, pepstatin. J. Immunol. 157:901-907, 1996.

152. Yamada, T., Miida, T., Itoh, Y., Kawai, T., and Benson, M.D.: Characterization of serum amyloid A4 as a plasma apolipoprotein. Clinica Chimica Acta 251:105-112, 1996.

153. Uemichi, T., Liepnieks, J.J., Yamada, T., Gertz, M.A., Bang, N., and Benson, M.D.: A frame shift mutation in the fibrinogen Aa chain gene in a kindred with renal amyloidosis. Blood 87:4197-4203, 1996.

154. Uemichi, T., Liepnieks, J.J., Waits, R.P., Benson, M.D.: A trinucleotide deletion in the transthyretin gene (DV122) in a kindred with familial amyloidotic polyneuropathy. Neurology 48:1667-1670, 1997.

155. Kluve-Beckerman, B., Yamada, T., Hardwick, J., Liepnieks, J.J., and Benson, M.D.: Differential plasma clearance of murine acute phase serum amyloid A proteins, SAA1 and SAA2. Biochem J. 322:663-669, 1997.

156. Benson, M.D. and Uemichi, T.: Transthyretin Amyloidosis. Amyloid: Int. J. Exp. Clin. Invest. 3:44-56, 1996.

157. Uemichi, T., Liepnieks, J.J., F. Alexander, and Benson, M.D.: The molecular basis of renal amyloidosis in Irish-American and Polish-Canadian kindreds. Q. J. Med. 89:745-750, 1996.

158. Cardinal, E., Buckwalter, K.A., Braunstein, E.M., Raymond-Tremblay, D., and Benson, M.D.: Amyloidosis of the shoulder in patients on chronic hemodialysis: Sonographic findings. American Journal of Roentology 166:153-156, 1996.

157. Burk, S.E., Benson, M.D., Jakobiec, F.A., Ceisler, E., Mukai, S.: Vitreous amyloidosis without transthyretin mutation. (Submitted).

160. Hamidi Asl, L., Liepnieks, J.J., Uemichi, T., Rebebou, J.M., Justrabo, E., Droz, D., Mousson, C., Chalopin, J.M., Benson, M.D., Delpech, M., and Grateau, G.: Renal amyloidosis with a frame shift mutation in fibrinogen Aa-chain producing a novel amyloid protein. Blood 90:4799-4805, 1997.

161. Klein, C.J., Nakamura, M., Jacobson, D.R., Lacy, M.Q., Benson, M.D., and Petersen, R.C.: Transthyretin amyloidosis (serine 44) with headache, hearing loss, and peripheral neuropathy. Neurology 51:1462-1464, 1998.

162. Goebel, H.H., Seddigh, S., Hopf, H.C., Uemichi, T., Benson, M.D., and McKusick, V.A.: A European family with histidine 58 transthyretin mutation in familial amyloid polyneuropathy. Neuromuscular Disorders 7:229-230, 1997.

163. Hamidi Asl, K., Liepnieks, J.J., Bihrle, R., and Benson, M.D.: Local synthesis of amyloid fibril precursor in AL amyloidosis of the urinary tract. Amyloid: Int. J. Exp. Clin. Invest. 5:49-54, 1998.

164. Kluve-Beckerman, B., Liepnieks, J.J., Wang, L. and Benson, M.D.: A cell culture system for the study of amyloid pathogenesis: Amyloid formation by murine peritoneal cells in the presence of recombinant serum amyloid A. Am. J. Pathol. 155:123-133, 1999.

165. Nakamura, M., Yamashita, T., Ando, Y., Hamidi Asl, K., Tashima, K., Ohlsson, P-I., Kususe, Y., and Benson, M.D.: Identification of a new transthyretin variant (Ile49) in familial amyloidotic polyneuropathy using electrospray ionization mass spectrometry and non-isotopic Rnase cleavage assay. Hum. Hered. 49:186-189, 1999.

166. Hamidi Asl, L., Liepnieks, J.J., Hamidi Asl, K., Uemichi, T., Moulin, G., Desjoyaux, E., Loire, R., Delpech, M., Grateau, G., and Benson, M.D.: Hereditary amyloid cardiomyopathy caused by a variant apolipoprotein A1. Am. J. Pathol. Am. J. Pathol. 154:221-227, 1999.

167. Uemichi, T., Liepnieks, J.J., Gertz, M.A., and Benson, M.D.: Fibrinogen Aa chain Leu554: An African-American kindred with late onset renal amyloidosis. Amyloid: Int. J. Exp. Clin. Invest. 5:188-192, 1998.

168. Wang, L., Kluve-Beckerman, B., Takasugi, K., Okuda, Y., Yamada, T., and Benson, M.D.: Human serum amyloid A1 allele frequencies and their relationship to the development of reactive amyloidosis in American Caucasian and Japanese populations. Submitted.

169. Mares, D.C., Broderick, L.S., Cummings, O.W., Benson, M.D., and Mathur, P.N.: Tracheobronchial amyloidosis: A review of clinical and radiographic characteristics, bronchoscopic diagnosis, and management. J Bronch 5:147-155, 1998.

170. Uemichi, T., Uitti, R.J., Koeppen, A.H., Donat, J.R., and Benson, M.D.: Oculo-leptomeningeal amyloidosis associated with a new transthyretin variant Ser64. Arch. Neurol. 56:1152-1155, 1999.

171. Hamidi Asl, K., Liepnieks, J.J., Nakamura, M., and Benson, M.D.: Organ specific (localized) synthesis of Ig light chain amyloid. J. Immunol. 162:5556-5560, 1999.

172. Wally, J., Kica, G., Zhang, Y., Ericsson, T., Connors, L., Benson, M.D., Liepnieks, J.J., Murray, J., Skinner, M., Comenzo, R.L.: Identification of a novel substitution in the constant region of a gene coding for an amyloidogenic kappa 1 light chain. Biochem. Biophys. Acta 1454:49-56, 1999.

173. Orpiszewski, J., and Benson, M.D.: Induction of b-sheet structure in amyloidogenic peptides by neutralization of aspartate: A model for amyloid nucleation. J. Mol. Biol. 289:413-428, 1999.

174. Nakamura, M., Hamidi Asl, K., and Benson, M.D.: A novel variant of transthyretin (Glu⁸⁹ to Lys) associated with familial amyloidotic polyneuropathy. Submitted.

175. Hamidi Asl, K., Liepnieks, J. J., Nakamura, M., Parker, F., and Benson, M.D.: A novel apolipoprotein A-1 variant, Arg173Pro, associated with cardiac and cutaneous amyloidosis. Biochem Biophys Res Commun 257:584-588, 1999.

176. Orpiszewski, J., and Benson, M.D.: Increase of b-sheet structure and amyloid deposition by spontaneous cyclization of aspartate to succinimide: A model for amyloid nucleation. Submitted.

177. Wang, L., Kluve-Beckerman, B., Liepnieks, J. J., and Benson, M.D.: Expression of apoSAACE/J and amyloidogenesis in congenic mice of CE/J and C57BL strains. Submitted.

178. Afolabi, I., Hamidi Asl, K., Nakamura, M., Jacobs, P., Hendrie, H., and Benson, M.D.: Transthyretin isoleucine-122 mutation in African and American Blacks. Amyloid: Int. J. Exp. Clin. Invest. In press.

179. Orpiszewski, J., Schormann, N., Kluve-Beckerman, B., Liepnieks, J. J., and Benson, M.D.: Protein aging hypothesis of Alzheimer disease. Submitted.

180. Schormann, N., and Benson, M..D.: Structural comparison of amyloidogenic light chain dimer in two crystal forms with nonamyloidogenic counterparts. Submmitted.

181. Serpell, L.C., Sunde, M., Benson, M.D., Pepys, M.B., and Fraser, P.E.: The supramolecular organization of protofilaments in amyloid fibrils. In preparation.

182. Hamidi Asl, K., Nakamura, M., Yamashita, T., and Benson, M.D.: Transthyretin cardiac amyloidosis associated with the Ile122 mutation in a Caucasian family. Submitted.

183. Benson, M.D.: Hereditary amyloidosis: some words on the history and present status of our eminent subject. Amyloid: Int. J. Exp. Clin. Invest. In press.

BOOKS & CHAPTERS:

1b. Benson, M.D.: The Comparative Pathology of Scurvy and Osteolathyrism. Master of Science Thesis (1964).

2b. Cohen, A.S. and Benson, M.D.: Amyloid Neuropathy. In Peripheral Neuropathy Ed. by Dyck, P.J., Thomas, P.K. and Lambert, E.H. 1067-1091. W.B. Saunders, Philadelphia, PA, 1975.

3b. Benson, M.D.: Allergy. In Medicine: Essentials of Clinical Practice, Ed. by Wilkins, R.W. and Levinsky, N.G. Second Edition 546-563. Little, Brown and Company, Boston, MA, 1978.

4b. Svartman, C., Masuda, A., Benson, M.D. and Scheinberg, M.A.: SAA Amyloid Protein Levels in Amyloid-Prone Chronic Inflammatory Disorders. In Amyloid and Amyloidosis, Ed. by Glenner, G. 38-42. Excerpta Medica, New York, NY, 1980.

5b. Benson, M.D.: Systemic Amyloidosis in an American Family of Swedish Origin: Histological and Biochemical Studies. In Amyloid and Amyloidosis, Ed. by Glenner, G. 86-87. Excerpta Medica, New York, NY, 1980.

6b. Benson, M.D.: Amyloidosis. In Principles of Rheumatic Diseases, Ed. by Panush, R.S. 367-376. John Wiley & Sons, New York, NY, 1981.

7b. Benson, M.D.: Pathogenesis of Amyloidosis. In Proceedings of the 7th Kal Kan Symposium, 47-52. 1983.

8b. Benson, M.D., Dwulet, F.E., Kluve-Beckerman, B. and Aldo-Benson, M.: Structure and Function of SAA. In Marker Proteins in Inflammation, Ed. by Laurent, P., Grimaud, J.A. and Bienvenu, J. Volume 3 Walter de Gruyter, Berlin, NY, 1985.

9b. Kluve-Beckerman, B., Benson, M.D., Dwulet, F.E., DiBartola, S.P. and Benson, M. Douglas: Phylogenetic Analysis of Amyloid A Protein. In Vth International Symposium on Amyloidosis, Hakone, Japan 1987.

10b. Wallace, M.R. and Benson, M.D.: DNA Tests for Four Prealbumin Mutations in Hereditary Amyloidosis. In Vth International Symposium on Amyloidosis, Hakone, Japan 1987.

11b. Benson, M.D., Dwulet, F.E., Madura, D. and Wheeler, G.: Structural analysis of a Lambda IV Primary Amyloid Protein. In Vth International Symposium on Amyloidosis, Hakone, Japan 1987.

12b. Kluve-Beckerman, B., Dwulet, F.E. and Benson, M.D.: Serum Amyloid A: Characterization of Three cDNAs in One Individual and Complete Structure of their Corresponding Protein Products. In Vth International Symposium on Amyloidosis, Hakone, Japan 1987.

13b. Benson, M.D.: Hereditary Amyloidosis - Disease Entity and Clinical Model. In Hosp. Pract. 23:165-181, 1988.

14b. Benson, M.D. and Wallace, M.R.: Amyloses Hereditaires: Acquisitions Recentes. Actualites Nephrologiques, de l' Hopital Necker. Flammarion Medecine-Sciences, 129-137. Paris, France 1988. (French)

14c. Benson, M.D. and Wallace, M.R.: Genetic Amyloidosis: Recent Advances. In Advances in Nephrology. Volume 33, 191-204. Year Book Medical Publishers, Chicago, IL, 1988.

15b. Benson, M.D. and Wallace, M.R.: Amyloidosis. In The Metabolic Basis of Inherited Disease, pp. 2439-2460. McGraw Hill Book Co., New York, NY, 1989.

16b. Benson, M.D.: Familial amyloidotic polyneuropathy. In Trends in Neurosciences. Volume 12, 88-92. Elsevier Science Publishers Ltd., UK, 1989.

17b. Benson, M.D.: Acute phase reactants. Curr. Opin. Rheumatol. 1:209-214, 1989.

18b. Benson, M.D.: Review article entitled "Inherited Amyloidosis" in Journal of Medical Genetics 28:73-78, 1991.

19b. Benson, M.D.: Chapter entitled "Hereditary Amyloidosis" in Molecular Basis of Neurology/Molecular Basis of Clinical Medicine, pp. 55-71. Ed. by P. Michael Conneally, Ph.D. Boston Blackwell Scientific Publications, Boston, MA.

20b. Husby, G., Araki, S., Benditt, E.P., Benson, M.D., Cohen, A.S., Frangione, B., Glenner, G.G., Natvig, J.B. and Westermark, P.: The 1990 Guidelines for nomenclature and classification of amyloid and amyloidosis, pp. 7-11. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/Boston/London.

21b. Kluve-Beckerman, B., Brinckerhoff, C. and Benson, M.D.: Sequence analysis of a third human SAA gene, pp. 24-27. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/Boston/London.

22b. Harats, N., DiBartola, S.P., Benson, M.D. and Kluve-Beckerman, B: Abyssinian cat model of AA amyloidosis: SAA gene analysis, pp. 32-35. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/Boston/London.

23b. Scheinberg, M.A., Chapira, E., Gordon de Carvalho, M., Mota, M.I. and Benson, M.D.: Interferon alfa induce TNF elevations in vivo. Correlation with other acute phase reactants, pp. 62-65. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/Boston/London.

24b. Quinn, L., Shafer, E., Liepnieks, J.J. and Benson, M.D.: Reactive (AA) amyloidosis in a 14 year old with no predisposing disease, pp. 91-94. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/ Boston/London.

25b. Kluve-Beckerman, B., Liepnieks, J. and Benson, M.D.: Differential regulation of human serum amyloid A isoforms, pp. 125-128. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/Boston/London.

26b. Liepnieks, J.J., Benson, M.D. and Dwulet, F.E.: Comparison of the amino acid sequences of ten kappa I amyloid proteins for amyloidogenic sequences, pp. 153-156. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/Boston/London.

27b. Liepnieks, J.J., Benson, M.D. and DiBartola, S.P.: Systemic AL amyloidosis in a cat, pp. 189-192. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/Boston/London.

28b. Benson, M.D., Rader, D.J., Schaefer, J.R., Gregg, R.E., Fairwell, T., Zech, L.A., Kindt, M.R., Brewer, Jr., H.B. and Meng, M.S.: In vivo metabolism of a mutant apolipoprotein A-I (Arg-26) associated with hereditary amyloidosis, pp. 381-384. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/ Boston/London.

29b. Benson, M.D.: Pathofibrillogenesis and amyloid proteins, pp. 481-486. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/Boston/London.

30b. Liepnieks, J.J., Leagre, C., Kluve-Beckerman, B. and Benson, M.D.: Predominance of one SAA isotype (SAAI) in human reactive amyloid, pp. 511-514. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/Boston/ London.

31b. Hamilton, J.A., Steinrauf, L.K., Liepnieks, J. and Benson, M.D.: X-ray crystal structure of the Met-30 variant of human prealbumin (transthyretin), pp. 579-582. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/Boston/London.

32b. Migita, S., Takegami, M. and Benson, M.D.: Disulfide bond formation of transthyretin (TTR) as possible initial step familial amyloid polyneuropathy (FAP), pp. 583-586. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/Boston/London.

33b. Murrell, J., Schoner, R., Moses, A., Rosen, H. and Benson, M.D.: Structure and function of recombinant human transthyretin, pp. 647-650. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/Boston/London.

34b. Martone, R.L., Benson, M.D. and Herbert, J.: Myelin P2 protein in transthyretin (Ser-84) vitreous amyloid, pp. 655-658. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/Boston/London.

35b. Scheinberg, M.A., Bakkenist, V.A. and Benson, M.D.: Cyclosporin reduces the incidence of amyloid disease in casein treated mice, pp. 874-882. In Amyloid and Amyloidosis 1990, VIth International Symposium on Amyloidosis, August 5-8, 1990, Oslo, Norway, Ed. by Jacob B. Natvig, Oystein Forre, Gunnar Husby, Anne Husebekk, Bjorn Skogen, Knut Sletten and Per Westermark. Kluwer Academic Publishers, Dordrecht/Boston/London.

36b. Benson, M.D.: Familial Amyloidoses. A review in the Journal of Internal Medicine, 232:525-527, 1992.

37b. Benson, M.D.: Amyloidosis. In The Metabolic and Molecular Bases of Inherited Disease, Seventh Edition, Volume III, Chapter 139, Part 18 Connective Tissues, pp. 4159-4191. Ed. by C.R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, McGraw Hill Book Co., New York, NY, 1995.

38b. Benson, M.D.: Hereditary amyloidosis and cardiomyopathy. An editorial on an article by Ranløv et al. appearing in the American Journal of Medicine, 93:1-2, 1992.

39b. Benson, M.D.: Commentary on article by John G. Rukavina et al. that appeared in Medicine in 1956: "Primary Systemic Amyloidosis: The Seeds of Our Present Research". Commentary to appear in "Classics in MEDICINE" section, 72:63-65, 1993.

40b. Ghetti, B., Farlow, M.R., Murrell, J., and Benson, M.D.: Guanine to thymine missense change at codon 717 of the APP gene: Further Characterization of an Alzheimer's Phenotype. In Alzheimer's Disease: Advances in Clinical and Basic Research, pp.227-234. Edited by B. Corain, K. Iqbal, M. Nicolini, B. Winblad, H. Wisniewski and P. Zatta. John Wiley & Sons Ltd., 1993.

41b. Hanes, D., Zech, L., Murrell, J.R., and Benson, M.D.: Metabolism of Normal and Met30 Transthyretin. In Advances in Food and Nutrition Research (Chapter 8 - Metabolism of Transthyretin) 40:149-155, 1996.

42b. Rosen, H.N., Moses A.C., Murrell, J.R., Liepnieks, J.J., and Benson, M.D.: Iodothyronine Analog Binding To (Thr¹⁰⁹) Transthyretin. In Progress in Thyroid Research, pp. 745-748. Edited by Gordon, Gross & Hennemann. Balkema, Rotterdam, 1991.

43b. Benson, M.D.: Familial Amyloidotic Polyneuropathy. In Peripheral Nerve, 5:41-45, 1994.

44b. Benson, M.D.: Commentary: Leptomeningeal Amyloid and Variant Transthyretins. Am. J. Pathol. 148:351-354, 1996.

45b. Benson, M.D.: Amyloidosis. In The Metabolic and Molecular Bases of Inherited Disease, Seventh Edition, Volume III, Chapter 139, Part 18 Connective Tissues, pp. 4159-4191. Ed. by C.R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, McGraw Hill Book Co., New York, NY, 1995.

46b. Benson, M.D.: Amyloidosis. In Arthritis and Allied Conditions - A Textbook of Rheumatology, 13th Edition, Volume Two, Chapter 86, pp. 1661-1687, 1996. Ed., W.J. Koopman, Williams & Wilkins, A Waverly Company.

47b. Benson, M.D.: Editorial: Aging, Amyloid and Cardiomyopathy. New England Journal of Medicine 336:502-504, 1997.

48b. Benson, M.D.: Editorial: Apolipoprotein AI and amyloidosis: A genetic model for aging. Kidney International 53: 508-509, 1997.

49b. Benson, M.D.: Amyloidosis. In Encyclopedia of Life Sciences, Chapter 2146. Submitted.

50b. Benson, M.D.: Amyloidoses. In Internal Medicine, 5th Edition, Chapter 210, pp. 1282-1285. Ed. by J. H. Stein, M.D., Mosby, Inc., St. Louis, MO, 1998.